Contact Infomation
Email: hhuarong@connect.hku.hk
Research interest
Immunotherapy has emerged as one of the most promising approaches for the treatment of infectious diseases, autoimmune diseases, and cancers over the past few decades. Specifically, I am highly interested in target discovery through gene editing and the development of immunotherapies based on the application of antibodies and T cells for immune-associated diseases.
Publication
First/Co-First author
(1) Huarong Huang, Shihua Li, Yongli Zhang, Xiaojuan Han, Baoqian Jia, Hongtao Liu, Dandan Liu, Shuguang Tan, Qihui Wang, Yuhai Bi, Baidong Hou, George Fu Gao*, and Fuping Zhang*, CD8+T cell immune response in immunocompetent mice during Zika virus infection, J Virol 2017; [citations>=128]
(2) Xiaojuan Han , Hongtao Liu #, Huarong Huang , Xinyuan Liu, Baoqian Jia, George Fu Gao, Fuping Zhang*, ID2 and ID3 are indispensable for Th1cell differentiation during influenza virus infection in mice, Eur J Immunol 2018; [citations>=20]
(3) Yimin Tang#, Juanjuan Zhang#, Huarong Huang, Xing He, Jiaohong Zhang, Min Ou, Guobao Li, Changchun Zeng, Taosheng Ye, Lili Ren, Yingxia Liu* and Guoliang Zhang*, Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion, BMC Infect Dis 2019; [citations>=28]
Co-author
(1) Xiaojuan Han, Huarong Huang, Ping Gao, Qi Zhang, Xinyuan Liu, Baoqian Jia, Warren Strober, Baidong Hou, Xuyu Zhou, George Fu Gao, Fuping Zhang*, E-protein regulatory network links TCR signaling to effector Treg cell differentiation, PNAS 2019; [citations>=15].
(2) Ping Gao, Hongtao Liu, Huarong Huang, Yu Sun, Baoqian Jia, Baidong Hou, Xuyu Zhou, Warren Strober* &Fuping Zhang*, The Crohn Disease-associated ATG16L1 T300A polymorphism regulates inflammatory responses by modulating TLR- and NLR-mediated signaling, Autophagy
2022; [citations>=29].
(3) Ping Gao, Hongtao Liu, Huarong Huang, Qi Zhang, Warren Strober, and Fuping Zhang*, The Inflammatory Bowel Disease–Associated Autophagy Gene Atg16L1T300A Acts as a Dominant Negative Variant in Mice, J Immunol, 2017; [citations>=29].
(4) Haoran Xu, Ming Yue, Runhong Zhou, Pui Wang, Michael Yik-Chun Wong, Jinlin Wang, Huarong Huang, Bohao Chen, Yufei Mo, Rachel Chun-Yee Tam, Biao Zhou, Zhenglong Du, Haode Huang, Li Liu, Zhiwu Tan, Kwok-Yung Yuen, You-Qiang Song, Honglin CHEN, and Zhiwei Chen*, A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells that Prevent Tumor Lung Metastasis. Cancer Research 2024;
(5) Yufei Mo, Ming Yue, Lok Yan Yim, Runhong Zhou, Chunhao Yu, Qiaoli Peng, Ying Zhou, Tsz-Yat Luk, Grace Chung-Yan Lui, Huarong Huang, Chun Yu Hubert Lim, Hui Wang, Li Liu, Hongzhe Sun, Jun Wang, Youqiang Song, Zhiwei Chen*, Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice. EBioMedicine 2023 [citations>=7].